Overview

Marijuana is produced by harvesting and desiccating the flowering buds and adjacent leaves of Cannabis sativa specimens. Medical marijuana lacks FDA approval, yet it’s legal in multiple states. The clash between federal and local policies persists, but acceptance grows

While maintaining its stance on cannabis, the FDA has sanctioned synthetic THC analogs including dronabinol and nabilone. Their primary applications involve treatment-resistant chemotherapy side effects, with dronabinol also approved for HIV-related appetite stimulation.

Additionally, Epidiolex a purified cannabidiol (CBD) solution has been approved by the FDA for treating two rare and severe epilepsy types in children: Lennox-Gastaut and Dravet syndromes.

Medical marijuana is available in various forms, including pills, oils, nasal sprays, vaporized liquids, dried plant material, and more. Among these options, many patients seek out uplifting cannabis varieties for daily use to help them maintain energy and focus while managing symptoms. It is commonly used to manage chemotherapy-related nausea, HIV-related weight loss, epilepsy, chronic pain, and muscle spasms.

What Research Shows

Scientific findings on marijuana’s effectiveness vary by condition:

• Glaucoma: Marijuana may lower intraocular pressure temporarily but could reduce blood flow to the optic nerve, possibly increasing vision risks.
• Chemotherapy patients: Research confirms that tetrahydrocannabinol (THC), marijuana’s primary psychoactive compound, provides effective antiemetic benefits against treatment-related nausea and vomiting.

• Chronic pain: It may help alleviate neuropathic pain, often linked to conditions like HIV and diabetes.
• Seizures: Research remains inconclusive regarding its effectiveness.
• Multiple Sclerosis (MS): It might ease muscle stiffness, spasms, and frequent urination associated with MS.

Caution Advised

Marijuana has shown effectiveness in treating chemotherapy-related nausea and MS symptoms, and in reducing nerve-related pain. However, it may impair cognition and judgment, particularly in those with mental health conditions. In many regions, it remains illegal.

Side Effects and Safety

Although often regarded as safe for medical use, marijuana strains vary in THC concentration, complicating accurate dosing. Common side effects include:

• Headache, dry mouth/eyes, dizziness, fatigue, and drowsiness
• Nausea, confusion, hallucinations, increased heart rate/appetite

Marijuana consumption may hinder memory, physical coordination, and clear thinking, creating hazards while operating vehicles or machines. Individuals with mental health disorders should use it cautiously, as it may worsen bipolar symptoms, increase depression risk, or trigger psychosis in people with schizophrenia.

Smoking marijuana may impair memory and cardiovascular health and aggravate lung conditions. Long-term use could result in respiratory complications.

It also acts as a central nervous system depressant and could intensify sedative effects when combined with anesthesia. Patients should discontinue marijuana use for a minimum of two weeks before any planned surgical procedure.

Potential Drug Interactions

Marijuana can interact with several substances:

• Alcohol: May amplify intoxicating effects
• Blood thinners: May interfere with how these drugs are processed, increasing the bleeding risk
• CNS depressants: Could intensify sedative effects
• Protease inhibitors: Might reduce their antiviral efficacy
• SSRIs (antidepressants): May increase the chance of manic episodes when used together